Set in Philadelphia, the show centers on a five year old boy named Little Bill Glover as he explores everyday life through his imagination. Little Bill lives with his mother and father, his great grandmother, his ten year old sister April, and his eight-year-old brother Bobby. At the end of every show, he breaks the fourth wall by summarising his day to the audience before going to bed. Sometimes, he even talks to his pet hamster, Elephant. Then, one of his family members says, "Little Bill, who are you talking to?". This was an ongoing catchphrase that closed every show.